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Your Dentist May Diagnose Systemic Disease Before Anyone Else.

World Health Organization defines oral health in terms of general, physical, psychological, and social well-being and teeth and gums speak a lot about the overall physiological well-being. The indication of our internal health can be examined through prominent changes in teeth, gums, or tongue. A similar indication has been seen in a case of tooth enamel defect related to renal disease called Nephrocalcinosis.


Recently, a patient reported at City Dental Clinic with the chief complaint of delayed eruption of upper front teeth. Based on oral examination, a tooth development disorder of Amelogenesis Imperfecta was anticipated. However, the symptoms of generalized Gingival Fibromatosis increased the probability of an underlying Renal Syndrome. Renal ultrasound ascertained the existence of Bilateral Nephrocalcinosis, a rare genetic kidney disease, which thereby confirmed the diagnosis of Enamel-Renal Syndrome.

Enamel formation or Amelogenesis is a systematic procedure of tooth enamel deposition. Any disorder in this procedure can lead to Tooth Discoloration, Hypocalcification, Hypomaturation, Fragility, Delayed/Unerupted Teeth, etc. It is monitored by genetic function due to which a genetic mutation is likely to inflict the disorder. It is an illness state known for too much deposition of calcium in kidneys in kinds of Calcium Oxalate and Calcium Phosphate. This procedure can impair kidney functions and can also cause kidney stones.

The probability of common genetic mutation makes it important to understand the disorders and their relationship. Systematic scoring of both tooth and kidney indications would help to differentiate both situations and will allow for early diagnosis. Hence, 

All patients with Amelogenesis Imperfecta are advised to have a detailed renal examination.

All patients with Nephrocalcinosis are advised to be referred for an oral examination.

 Oral Health and Overall Health have a synergistic and dynamic relationship and regular dental check-ups from experienced dentists can help a lot in maintaining good oral and overall health and be aware of apparent ailments prevailing in the body. Book your appointment at the best DentalClinic in Noida- City Dental Clinic which has the best-in-class facilities for you and your loved ones.

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  1. Renee YurovskySeptember 29, 2021 at 4:20 PM

    Thanks for always taking the time to share this informative information with us. I always enjoy stopping by your blog for articles. Have a great rest of your day.
    Dentist Philadelphia

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